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One study compared the effectiveness of Curcumin the active ingredient in turmeric and a popular non-steroidal anti-inflammatory drug (NSAID) called phenylbutazone.At the end of the six days, those taking the Curcumin and the NSAID enjoyed a significantly better anti-inflammatory response than placebo. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.And its no wonder considering six major scientific trials all found curcumin to possess a potent anti-inflammatory action, which is completely non-toxic in nature.A study evaluating several pharmaceutical anti-inflammatories found that aspirin and ibuprofen are the potent, while curcumin is among the most potent anti-inflammatory and anti-proliferative agents available.
The high concentrations of curcumin contained in turmeric act to target multiple steps in the inflammatory pathway, blocking inflammatory markers at the molecular level and thereby significantly lowering long-term inflammation in your body.
Turmeric is a member of the Curcuma botanical group, which is part of the ginger family of herbs, the Zingiberaceae.
The root and rhizome stem of the Curcuma longa plant is crushed and powdered into ground Turmeric spice.
The spice worked as well as the drug, but without the negative side effects. Curcumin has also been shown to inhibit mediators of the inflammatory response, including cytokines, chemokines, adhesion molecules, growth factors, and enzymes like cyclooxygenase (COX), lipoxygenase (LOX), and inducible nitric oxide synthase (i NOS).
Nuclear factor-kappa B (NF-κB) is a transcription factor that binds DNA and induces the transcription of the COX-2 gene, other pro-inflammatory genes, and genes involved in cell proliferation, adhesion, survival, and differentiation.